Maximum-Strength Prescription Gel for Stubborn, Hormonal, and Resistant Acne

Maximum-Strength Prescription Gel for Stubborn, Hormonal, and Resistant Acne

Severe, stubborn acne? This prescription-strength gel with benzoyl peroxide, clindamycin, niacinamide, and tretinoin fights bacteria, clears pores, and prevents

1 Big Thing

Struggling with persistent, cystic, or treatment-resistant acne? Onzdeaxiavar Gel, a high-potency prescription formula with Benzoyl Peroxide (5%), Clindamycin (1%), Niacinamide (2%), and Tretinoin (0.05%), is designed to clear deep breakouts, kill acne-causing bacteria, regulate oil, and accelerate skin renewal—helping you achieve long-term clarity.

Why It Matters

Most acne treatments only target one or two causes of breakouts, but stubborn, hormonal, and deep inflammatory acne require a stronger, multi-action solution. Onzdeaxiavar Gel combines four dermatologist-trusted ingredients to eliminate acne bacteria, prevent clogged pores, calm inflammation, and promote healthy skin turnover.

Between the Lines

If your acne is severe, prone to scarring, or unresponsive to drugstore treatments, this prescription gel is designed to stop acne at its source and prevent future breakouts.

Go Deeper

Why Is Acne So Hard to Treat?

Acne is a complex skin condition that occurs when multiple triggers interact, including:

  • Excess Oil Production – Overactive sebaceous glands trap bacteria and dead skin, clogging pores.
  • Bacterial Overgrowth (C. acnes) – Trapped bacteria cause inflammation, leading to painful, pus-filled breakouts.
  • Slow Skin Cell Turnover – Dead skin cells don’t shed properly, leading to blackheads and whiteheads.
  • Chronic Inflammation & Sensitivity – The immune system worsens acne by increasing redness and swelling.

👉 Onzdeaxiavar Gel treats all four causes of acne, helping to clear breakouts and prevent future flare-ups.

How the Benzoyl Peroxide + Clindamycin + Niacinamide + Tretinoin Formula Works

Onzdeaxiavar Gel is a powerful prescription acne treatment that fights bacteria, unclogs pores, reduces oil, and repairs skin for long-term acne relief.

Key Ingredients & Their Role

1. Benzoyl Peroxide (5%) – The Bacteria & Oil Eliminator

Benzoyl Peroxide is one of the most effective topical acne-fighting agents, working by:

  • Killing acne-causing bacteria on contact, preventing new breakouts.
  • Dissolving excess oil, reducing shine and clogged pores.
  • Preventing antibiotic resistance, making it an ideal partner for Clindamycin.

👉 At 5%, this is the strongest non-prescription benzoyl peroxide concentration, ensuring powerful acne-fighting action.

2. Clindamycin (1%) – The Anti-Inflammatory Antibiotic

Clindamycin is a prescription topical antibiotic that:

  • Kills acne bacteria, reducing the severity of breakouts.
  • Calms redness and inflammation, helping active breakouts shrink faster.
  • Works synergistically with Benzoyl Peroxide, enhancing its effectiveness.

👉 Clindamycin + Benzoyl Peroxide is a clinically proven combination for treating moderate to severe acne.

3. Niacinamide (2%) – The Oil-Regulating & Skin-Soothing Agent

Niacinamide (Vitamin B3) is a multi-functional skincare powerhouse that:

  • Balances oil production, preventing clogged pores and excessive shine.
  • Reduces redness and irritation, soothing inflamed acne.
  • Strengthens the skin barrier, improving hydration and resilience.

👉 Niacinamide ensures acne treatment is effective while reducing dryness or irritation.

4. Tretinoin (0.05%) – The Skin Renewal & Acne Prevention Retinoid

Tretinoin is a gold-standard prescription retinoid that:

  • Speeds up skin cell turnover, preventing new clogged pores and breakouts.
  • Fades acne scars and post-inflammatory hyperpigmentation, leading to a smoother complexion.
  • Boosts collagen production, reducing long-term scarring from severe acne.

👉 At 0.05%, this is a high-strength tretinoin concentration for effective skin renewal and acne control.

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Effectiveness & Considerations

  • Targets moderate to severe acne, including inflamed, cystic, and treatment-resistant breakouts.
  • Works best for those struggling with multiple acne triggers, such as excess oil, bacteria, and slow cell turnover.
  • Requires consistency—visible improvements take time, but the long-term benefits are significant.
  • Common side effects: Mild peeling, temporary purging (initial breakouts), or dryness as the skin adjusts.

👉 A "retinoid purge" may occur in the first few weeks as Tretinoin clears out clogged pores—this is normal and temporary.

Results Timeline

  • Week 1-2 – Oil production stabilizes, and the skin may begin purging (temporary breakout phase).
  • Week 3-4 – Active breakouts shrink, and inflammation decreases.
  • Week 5-8 – Significant reduction in acne, improved skin texture, and fewer new breakouts.
  • Beyond Week 8 – Long-term acne prevention and clearer, healthier skin.

👉 With continued use, Onzdeaxiavar Gel prevents acne while improving overall skin health and resilience.

How to Use Onzdeaxiavar Gel for Acne

For best results, follow these application guidelines:

  1. Apply a pea-sized amount to clean, dry skin once daily at night.
  2. Gently spread over affected areas, avoiding eyes, lips, and broken skin.
  3. Follow with a moisturizer to maintain hydration and reduce sensitivity.
  4. Always wear sunscreen (SPF 30+), as Tretinoin and Benzoyl Peroxide increase sun sensitivity.
  5. Stick with the treatment—visible improvement takes time but leads to lasting results.

👉 Best for: Moderate to severe acne, inflamed breakouts, and acne-prone skin.
👉 Not for: Extremely sensitive or rosacea-prone skin—consult a specialist before use.

Why Choose a Compounded Formula?

Unlike standard acne treatments, this custom-compounded prescription formula is:

  • More effective than OTC options, combining four prescription-strength ingredients for superior acne control.
  • Designed for acne-prone skin, offering both bacteria-fighting power and soothing properties.
  • Prescribed by medical professionals, ensuring safe and optimal results.

👉 This treatment requires a prescription, which Well Revolution can provide.

What Are the Alternatives?

If you're considering other acne treatments, here are some alternatives:

  • Lower-Strength Retinoids (Adapalene 0.1%, Tretinoin 0.025%) – Good for mild acne but less potent than prescription-strength 0.05%-0.1% Tretinoin.
  • Salicylic Acid Cleansers – Can help unclog pores, but won’t clear deep, inflamed breakouts.
  • Over-the-Counter Benzoyl Peroxide (2.5%-5%) – Useful for mild acne but lacks the added power of prescription Clindamycin and Tretinoin.
  • Oral Antibiotics (Doxycycline, Minocycline) – Can work for moderate to severe acne but may cause bacterial resistance over time.
  • Hormonal Acne Treatments (Spironolactone, Birth Control Pills) – Effective for hormonal breakouts but require systemic use and medical supervision.
  • Isotretinoin (Accutane) – The strongest acne treatment for severe cystic acne, but requires strict medical monitoring and has significant side effects.
  • Professional Procedures (Chemical Peels, Laser Therapy, Microneedling) – Can help improve skin texture and reduce acne scars, but require multiple in-office sessions and are costly.

👉 For most cases of moderate to severe acne, prescription-strength Onzdeaxiavar Gel provides one of the best topical treatments available.

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Steps to Get Your Acne Treatment Prescription

1. Free Specialist Consultation

Chat live with a Well Revolution specialist to assess your acne type and severity. A quick assessment will help establish which treatment is right for you.

2. Get a Custom Prescription

If treatment is recommended, get a prescription for a custom-compounded formula for just $50.

3. Get Your Treatment

Your prescription is sent to a Well Revolution pharmacy partner for home delivery or pickup.

Prescription-Strength Treatment for Maximum Acne Control

Acne isn’t just about breakouts—it’s about skin health and confidence. Onzdeaxiavar Gel is a dermatologist-trusted, prescription-strength solution that eliminates bacteria, prevents future breakouts, and improves skin texture for long-term clarity.

👉 Health concerns, no matter how minor, can impact your confidence and overall well-being. If you're ready to take control of acne, consult a Well Revolution specialist today for expert guidance and a personalized treatment plan.

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