Brighten and Correct: Expert Pigmentation Repair

1 Big Thing

Struggling with dark spots that won’t fade? A prescription-strength formula with tretinoin (0.05%), hydroquinone (4%), and kojic acid (4%) is designed to target stubborn pigmentation and even out skin tone.

Why It Matters

Dark spots, hyperpigmentation, and uneven skin tone can be frustrating and resistant to regular skincare products. This dermatologist-trusted formula works to fade discoloration at the source—correcting pigmentation and revealing brighter, more even skin.

Between the Lines

Many over-the-counter products promise results, but without prescription-strength ingredients, they often fall short. This clinically backed formula is designed for stubborn hyperpigmentation, melasma, and post-inflammatory dark spots.

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Go Deeper

Why Does Skin Discoloration Happen?

Hyperpigmentation happens when excess melanin (the pigment that gives skin its color) builds up in certain areas, leading to dark patches. The most common causes include:

• Sun Damage – UV exposure increases melanin production, leading to sunspots.
• Hormonal Changes – Pregnancy, birth control, and menopause can trigger melasma.
• Post-Inflammatory Hyperpigmentation (PIH) – Acne scars, bug bites, and skin irritation can leave behind stubborn dark spots.
• Genetics – Some people are naturally more prone to uneven pigmentation.

👉 Dark spots won’t fade on their own—without proper treatment, they can linger for months or even years.

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How the Tretinoin + Hydroquinone + Kojic Acid Formula Works

This prescription-only topical treatment combines three clinically proven ingredients to brighten, exfoliate, and fade dark spots at the cellular level.

Key Ingredients & Their Role

1. Tretinoin (0.05%) – The Skin Cell Accelerator

Tretinoin is a powerful vitamin A derivative (retinoid) that speeds up skin cell turnover, helping fade dark spots faster. It works by:

• Removing old, pigmented skin cells and bringing new, even-toned cells to the surface.
• Boosting collagen production, improving skin texture and elasticity.
• Enhancing the absorption of other active ingredients for maximum effectiveness.

👉 Tretinoin can cause mild peeling and irritation at first, but this is part of the skin renewal process.

2. Hydroquinone (4%) – The Gold-Standard Skin Brightener

Hydroquinone is the most effective skin-lightening agent available by prescription. It works by:

• Blocking melanin production to prevent new dark spots.
• Breaking down existing pigmentation, gradually fading dark patches.
• Working best when combined with tretinoin, which enhances its penetration.

👉 Hydroquinone is a short-term treatment—it should be used for 3-4 months at a time, followed by a break to prevent skin tolerance.

3. Kojic Acid (4%) – The Natural Pigment Inhibitor

Kojic acid is a gentle yet effective brightening agent derived from fungi. It works by:

• Inhibiting tyrosinase, an enzyme responsible for melanin production.
• Enhancing the effects of hydroquinone, making it more effective.
• Providing antioxidant benefits, helping to repair sun damage.

👉 Kojic acid is naturally soothing, helping to minimize irritation from tretinoin and hydroquinone.

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Effectiveness & Considerations

• Targets multiple causes of hyperpigmentation—not just surface-level discoloration.
• Works best for melasma, sunspots, and post-acne dark marks.
• Full results take 8-12 weeks of consistent use.
• Common side effects: Mild irritation, peeling, or temporary redness.

👉 This formula is NOT a spot treatment—it should be applied evenly to affected areas to prevent uneven lightening.

Results Timeline

• Week 1-4 – Skin begins adjusting, mild peeling and irritation may occur.
• Week 5-8 – Dark spots gradually start to fade, skin looks brighter.
• Week 9-12 – Full results appear, with significantly clearer, more even skin.

How to Use the Tretinoin + Hydroquinone + Kojic Acid Cream

For best results, follow these application guidelines:

1. Apply a pea-sized amount only to affected areas—not your whole face.
2. Use at bedtime—these ingredients increase sun sensitivity.
3. Wait 20-30 minutes after washing your face before applying.
4. Follow with a gentle moisturizer to reduce dryness.
5. Always wear sunscreen (SPF 30+) during the day—sun exposure can reverse progress.
6. Limit use to 3-4 months at a time before taking a break.

👉 Best for: Stubborn hyperpigmentation, melasma, and dark spots that don’t respond to OTC products.
👉 Not for: Inflamed acne or highly sensitive skin (may cause excessive irritation).

Why Choose a Compounded Formula?

Unlike store-bought brightening creams, a custom-compounded prescription formula is:

• Stronger and more effective – Uses clinical-grade ingredients proven to fade dark spots.
• Custom-tailored – Balances skin renewal, brightening, and anti-inflammatory support.
• Prescribed by medical professionals – Ensuring safety and effectiveness.

👉 This treatment requires a prescription, which Well Revolution can provide.

What Are the Alternatives?

If you’re looking for other ways to treat hyperpigmentation, consider:

• Vitamin C Serums – Provide antioxidant support but work more slowly.
• Niacinamide – Helps brighten skin but is not as powerful as hydroquinone.
• Azelaic Acid – A milder option for sensitive skin.
• Chemical Peels & Laser Treatments – Faster results but require downtime and professional treatments.

👉 For most people, a prescription topical formula is the best non-invasive first-line treatment.

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Steps to Get Your Skin Brightening Prescription

1. Free Specialist Consultation

Chat live with a Well Revolution licensed specialist to assess your skin concerns. A quick assessment will help establish which treatment is right for you.

2. Get a Custom Prescription

If treatment is recommended, get a prescription for a custom-compounded formula for just $50.

3. Get Your Treatment

Your prescription is sent to a Well Revolution pharmacy partner for home delivery or pickup.

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Brighter, More Even Skin

Hyperpigmentation can be stubborn and difficult to treat, but with the right prescription-strength ingredients, you can fade dark spots and even out your skin tone.

With consistent use, expert guidance, and a dermatologist-trusted formula, you can achieve brighter, healthier-looking skin—without expensive laser treatments or ineffective OTC products.

Health concerns, no matter how minor, can impact your confidence and overall well-being. If you're ready to correct skin discoloration, consult a Well Revolution primary care provider today for expert guidance and a personalized treatment plan.

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