Is My Anal Fissure Serious? Understanding Symptoms, Warning Signs and How to treat
Anal fissures can be painful but usually heal with simple care. Learn the signs that need more attention.

Anal fissures can be painful but usually heal with simple care. Learn the signs that need more attention.

Anal fissures, while not life-threatening, can cause significant discomfort. Most heal with basic care but persistent cases may need more attention.
For those affected, managing symptoms effectively is crucial for maintaining quality of life and preventing complications.
If an anal fissure doesn't improve, it might signal an underlying condition needing further evaluation (Wald et al., 2021).
An anal fissure is essentially a small tear in the lining of the anus. Although it might not sound serious, this condition can cause intense pain, especially during and after bowel movements. Patients often describe this pain as a "cutting" or "tearing" sensation, and it is usually accompanied by bright red blood on toilet paper. Fortunately, most fissures heal on their own with proper personal care (Wald et al., 2021).
However, when a fissure becomes chronic, which means it lasts longer than eight to twelve weeks, additional symptoms might appear, such as a skin tag near the tear, known as a sentinel pile. Sometimes, the fissure might not heal due to underlying conditions like Crohn’s disease or infections, evidenced by systemic symptoms such as fever or weight loss (Rao et al., 2022).
For typical, acute anal fissures, conservative management is usually effective. This involves increasing dietary fiber intake, staying well-hydrated, and taking sitz baths to soothe the area. Such treatments can heal about half of all fissures (Tarasconi et al., 2021). Topical anesthetics can also provide pain relief.
When these measures don't result in improvement, especially in chronic fissures, the next step often involves topical treatments.
Calcium channel blockers like diltiazem or nifedipine are frequently recommended due to their ability to relax the anal sphincter muscle, reducing pain and aiding healing. These treatments are well-tolerated with fewer side effects compared to other options like nitroglycerin ointment, which can cause headaches (Wang et al., 2025).
Most anal fissures are benign, yet some signs indicate a need for deeper investigation. Fissures that persist despite treatment, deviate from the midline, or show additional concerning signs like unexplained weight loss or persistent pain must be evaluated for possible underlying causes like systemic diseases or malignancy (Mathur et al., 2020).
In specific cases where conservative and topical treatments fail or when quicker relief is necessary, botulinum toxin injections may offer an alternate route. Though not FDA-approved for anal fissures, it's used off-label to temporarily relieve sphincter muscle tightness (Nelson et al., 2012).
Surgery, specifically lateral internal sphincterotomy, may be considered for fissures resistant to medical therapy. This procedure provides the highest healing rate but carries a risk of minor incontinence, so it’s only recommended when all other options have been exhausted (Boland et al., 2020).
Choosing the right treatment approach depends on various factors, including the severity of the fissure, how long it has persisted, and individual patient preferences and needs. Health providers aim to balance effective healing with minimizing complications (Sierra-Arango et al., 2023).
While it can be challenging to prevent a fissure from occurring initially, some lifestyle modifications can minimize recurrence. Maintaining a diet high in fiber and fluids can promote easier, less painful bowel movements. Regular exercise and avoiding straining during defecation also support overall bowel health and reduce the likelihood of fissures forming again (Jin et al., 2022).
Health concerns, no matter how minor they may seem, can severely impact your overall well-being and quality of life. If you're experiencing symptoms or have concerns about a specific health condition, remember that timely and expert advice is key. Navigating healthcare can be challenging, but finding the right primary care physician shouldn't be. Whether you're seeking medical advice, a prescription or care, immediate access to expert primary care is just a button away. Don't leave your health to chance - consult a Well Revolution primary care provider today for peace of mind and professional care.
1. Wald A, Bharucha AE, Limketkai B, et al. ACG Clinical Guidelines: Management of Benign Anorectal Disorders. The American Journal of Gastroenterology. 2021;116(10):1987-2008. doi:10.14309/ajg.0000000000001507.
2. Rao SSC, Qureshi WA, Yan Y, Johnson DA. Constipation, Hemorrhoids, and Anorectal Disorders in Pregnancy. The American Journal of Gastroenterology. 2022;117(10S):16-25. doi:10.14309/ajg.0000000000001962.
3. Tarasconi A, Perrone G, Davies J, et al. Anorectal Emergencies: WSES-AAST Guidelines. World Journal of Emergency Surgery : WJES. 2021;16(1):48. doi:10.1186/s13017-021-00384-x.
4. Wang C, Ni J, Xiong Y, et al. The Efficacy of Diltiazem, Glyceryl Trinitrate, Nifedipine, Minoxidil, and Lidocaine for the Medical Management of Anal Fissure: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. International Journal of Surgery (London, England). 2025;111(4):3020-3029. doi:10.1097/JS9.0000000000002263.
5. Mathur N, Qureshi W. Anal Fissure Management by the Gastroenterologist. Current Opinion in Gastroenterology. 2020;36(1):19-24. doi:10.1097/MOG.0000000000000599.
6. Nelson RL, Thomas K, Morgan J, Jones A. Non Surgical Therapy for Anal Fissure. The Cochrane Database of Systematic Reviews. 2012;(2):CD003431. doi:10.1002/14651858.CD003431.pub3.
7. Sierra-Arango F, de la Hoz-Valle J, Espinosa JP, et al. Clinical Outcomes of Medical Management Options for Chronic Anal Fissures in a Long-Term Follow-Up: Systematic Review and Meta-Analysis. Digestive Diseases (Basel, Switzerland). 2023;41(5):822-832. doi:10.1159/000528222.
8. Jin JZ, Hardy MO, Unasa H, et al. A Systematic Review and Meta-Analysis of the Efficacy of Topical Sphincterotomy Treatments for Anal Fissure. International Journal of Colorectal Disease. 2022;37(1):1-15. doi:10.1007/s00384-021-04040-3.
9. Boland PA, Kelly ME, Donlon NE, et al. Management Options for Chronic Anal Fissure: A Systematic Review of Randomised Controlled Trials. International Journal of Colorectal Disease. 2020;35(10):1807-1815. doi:10.1007/s00384-020-03699-4.
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